Molecular Formula | C8H16N2O2 |
Molar Mass | 172.22 |
Density | 1.1g/ml |
Boling Point | 79-81 3mm |
Flash Point | 96.9°C |
Solubility | DMSO, Methanol, Water |
Vapor Presure | 0.0468mmHg at 25°C |
Appearance | Oil |
Color | Clear Colourless to Pale Yellow |
pKa | 8.29±0.20(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Refractive Index | 1.4650 |
MDL | MFCD01861753 |
Risk Codes | R34 - Causes burns R51 - Toxic to aquatic organisms R22 - Harmful if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
UN IDs | 2735 |
HS Code | 29339900 |
Hazard Note | Irritant |
Hazard Class | 8 |
Packing Group | Ⅲ |
use | azacyclobutane compounds are widely used as pharmaceutical intermediates and receive attention. In recent years, a large number of new compounds have been successfully prepared and tested through various functional group modifications, many of which have good pharmaceutical activity. For example, 1-diphenylmethyl-3-aminoazetane and 1-diphenylmethyl-3-hydroxy-3-aminomethylazetane have been used in the synthesis of some antibacterial and antidepressant drugs in recent years. 1-tert-butoxycarbonyl-3-aminocyclobutylamine is also an important pharmaceutical intermediate used in the synthesis of IRAK-4 inhibitors. |